U.S. Numbered Highway System

Explore the U.S. Numbered Highway System—historic routes, major corridors, and scenic roads connecting every region of the country. Learn more about U.S. Highways across America.

The U.S. Numbered Highway System—often referred to as U.S. Routes or U.S. Highways—is a nationwide network of roads established in 1926 to improve long-distance automobile travel across the United States. Unlike the Interstate system, U.S. Highways predate freeways and often serve as main streets, scenic byways, or vital connectors through rural and urban communities alike. Many historic routes, including iconic roads like U.S. Route 66, trace their roots to this enduring network.

These highways use a grid system for numbering: odd-numbered routes run north–south, increasing from east to west, while even-numbered routes run east–west, increasing from north to south. Important cross-country highways typically end in “0” or “1” (like US 20 or US 1), and three-digit offshoots usually indicate spurs or loops branching from mainline routes.

Today, the U.S. Highway system continues to evolve—some segments have been decommissioned, realigned, or upgraded to freeways—but many routes remain essential for regional travel, trucking, and scenic exploration. This category explores the entire U.S. Numbered Highway network, from coast to coast and border to border.

Discover U.S. Routes

U.S. Route 64: Lakeland to Bartlett – Tennessee

U.S. Route 64: Lakeland to Bartlett – Tennessee

Cruise 6 miles west on U.S. Route 64 from Lakeland to Bartlett, TN. Pass I-40 and Wolfchase before ending at US-70/US-79. Suburban growth meets highway convenience on this short Memphis metro drive.

U.S. Route 65: Branson to Arkansas – Missouri

U.S. Route 65: Branson to Arkansas – Missouri

ChatGPT said: Take a high-speed plunge from the entertainment capital of the Ozarks into the quiet hills of the Missouri-Arkansas border as we travel U.S. Route 65 from Branson to the Natural State. This 11-mile drive showcases the dramatic transition from bustling…

U.S. Route 412: Jackson to Bells – Tennessee

U.S. Route 412: Jackson to Bells – Tennessee

Take a 10-mile drive on U.S. Route 412 from Jackson to Bells, Tennessee, transitioning from suburban Jackson to the farmlands of Crockett County. Explore rural scenery and local character along this westbound highway route.

U.S.Route 45 BYP: Jackson – Tennessee

U.S.Route 45 BYP: Jackson – Tennessee

Take a quick but crucial loop around the western side of Jackson, Tennessee, as we follow the 5-mile U.S. Route 45 Bypass—a route engineered to keep through-traffic flowing while offering convenient access to one of West Tennessee’s busiest regional hubs. This short…

U.S. Route 70: Jackson – Tennessee

U.S. Route 70: Jackson – Tennessee

Follow U.S. Route 70 for 8 miles through Jackson, Tennessee, as it loops from US-412 on the northeast side of town to US-45 Bypass on the west, connecting key corridors and neighborhoods along the way.

U.S. Route 72: Florence to Sheffield – Alabama

U.S. Route 72: Florence to Sheffield – Alabama

Take a short but scenic drive across the Tennessee River as we follow U.S. Route 72 from downtown Florence to Sheffield, Alabama—passing through a region rich in music history and Southern charm.

U.S. Route 72: Tuscumbia to Florence – Alabama

U.S. Route 72: Tuscumbia to Florence – Alabama

Take a scenic 6-mile drive along U.S. Route 72 from Tuscumbia to Florence, Alabama, crossing the Tennessee River and passing through the heart of the Muscle Shoals region—rich with music history and Southern charm.

U.S. Route 72: Cherokee to Tuscumbia – Alabama

U.S. Route 72: Cherokee to Tuscumbia – Alabama

Take a scenic drive along U.S. Route 72 from Cherokee to Tuscumbia, Alabama. This 24-mile route winds through Barton and past AL-247, ending at US-43 in historic Tuscumbia. Explore the quiet beauty and local heritage of northwest Alabama.

U.S. Route 61: Natchez – Mississippi

U.S. Route 61: Natchez – Mississippi

Take a short but scenic ride along US-61 through historic Natchez, Mississippi. This 3-mile stretch connects U.S. 425 to the Natchez Trace Parkway, offering a glimpse into the cultural and geographic heart of southwest Mississippi.

U.S. Route 425: Natchez – Mississippi

U.S. Route 425: Natchez – Mississippi

Take a brief but meaningful drive along U.S. Route 425 through Natchez, Mississippi, as we follow this 2-mile segment from Canal Street to its southern end at US-61—linking downtown charm with a gateway to the Delta.